Purpose

A junior lab-based role focused on supporting the wider R&D team, contributing to the characterisation of antibody hits and identification of lead candidates to meet the objectives of the Company’s R&D plan. The Associate Scientist will collaborate with the R&D team to culture primary and transformed cell lines, as well as develop and execute cell-based assays to support the R&D workflow. This includes performing established SOPs to support screening of novel hits using biologics i.e. monoclonal antibodies and bispecifics, as well developing complex assays using primary immune cells, to support the translation and determine the mechanisms of action of therapeutic antibodies and their effects on the function of innate and adaptive immune cells in healthy and disease settings. This role is primarily laboratory based, and training will be provided where required. This is an exciting opportunity to join a small, fast paced team that is dedicated to delivering next generation therapeutics to patients.

Key Accountabilities:

• Supporting the smooth running of the laboratory by performing cell culture, banking cell lines and isolation of primary immune cells from whole blood
• Support development of complex co-culture assays to explore functional and phenotypic responses of novel therapeutic antibodies
• Contribute to building work packages to support agreed timelines and objectives by performing and analysing in vitro assays
• Support complex scientific research of R&D team by generating data and presenting to the wider team on a regular basis
• Proactively support the whole R&D team and actively contribute to the smooth running of the laboratory

Education/Experience:

• BSc/MSc in relevant biological discipline (e.g. Immunology, Cell Biology) with at least one year lab experience (academic or industry)
• Experience working in a company setting (Biotech or Pharma) strongly preferred
• Previous experience performing cell culture, including primary cells
• Previous experience of flow cytometry preferred
• Understanding of Oncology and Immunology preferred

Skills/Competencies:

• Isolating, culturing and working with primary human cells
• Performing flow cytometry and cell based functional assays
• Commitment to high-quality research standards, with attention to detail and data integrity and excellent record keeping
• Enjoys working in a fast moving, dynamic start-up environment
• Flexible, pragmatic and practical, highly motivated to ensure that studies meet challenging timelines and able to propose practical, compromise solutions to problems
• Willing to take the initiative, planning and implementing work
• Willing to work as part of a small team, engaging constructively with colleagues at all levels to deliver objectives, both for individual work and to help problem solving across the R&D team
• Willing to comply with Health and Safety standards and Standard Operating Procedures and Policies
• Willing and able to work flexible hours when required.

Organisational Responsibilities:

The Associate Scientist will report into a Senior Scientist in the R&D team. There are no roles reporting into the Associate Scientist role.

Notes:

Strictly no agencies.

Candidates are required to demonstrate they hold the right to work in the UK.

This is a full-time laboratory-based role, 5 days a week in Canary Wharf in London.

Please send CV and cover letter to jobs@cytospiretx.com

Whilst we will attempt to respond to applicants, this may not be possible and if applicants have not heard from us within 6 weeks, they should assume they have not been successful on this occasion.