CAREERS
Strictly no agencies, please.
Associate Scientist/Scientist
The individual will utilise their scientific expertise (both theoretical and practical) to support the delivery of the company’s R&D objectives. The scientist will have a good understanding of immunology and experience developing complex immunology assays using primary immune cells. The Scientist is responsible for independently designing, executing and analysing in vitro experiments resulting in the delivery of high-quality work packages and will demonstrate scientific rigor and critique of their work. This includes performing established SOPs, as well as assay development and optimisation to support the screening of novel biologics i.e. monospecific and multi-specific antibodies. Their work will also support the translation and determine the mechanisms of action of novel therapeutics on the function of innate and adaptive immune cells in healthy and disease settings. This role is primarily laboratory based, and training will be provided where required. This is an exciting opportunity to join a small, fast paced team that is dedicated to delivering next generation immune cell engagers to patients.
Key Accountabilities:
• Independently perform, analyse and interpret experiments to deliver work packages to meet agreed objectives
• Consistently producing high quality data to support portfolio programs and enable decision making
• Support assay development and data package delivery for both immunology and translational focused assays
• Actively contribute to the smooth running of the laboratory e.g. by performing cell culture, banking cell lines and isolation of primary immune cells from whole blood
• Support the development of complex co-culture assays to explore functional and phenotypic responses of novel therapeutic antibodies
• Support complex scientific research of R&D team by generating data and presenting to the wider team on a regular basis
• Proactively seeking to support delivery from the whole R&D team
Education/Experience:
• PhD in relevant biological discipline or MSc (eg Immunology or Cell Biology) with at least three years of relevant laboratory-based experience.
• Experience working in a company setting (Biotech or Pharma) strongly preferred
• Experience in immunology research across a range of immune cell subtypes. Expertise in innate immunology specifically gamma delta T cell biology would be advantageous
• Strong understanding and experience of biologics drug discovery
• Strong understanding of oncology and/or immunology essential
• Experience of working in a fast moving, dynamic (e.g. small company or start-up) environment preferreKey Accountabilities:
• Independently perform, analyse and interpret experiments to deliver work packages to meet agreed objectives
• Consistently producing high quality data to support portfolio programs and enable decision making
• Support assay development and data package delivery for both immunology and translational focused assays
• Actively contribute to the smooth running of the laboratory e.g. by performing cell culture, banking cell lines and isolation of primary immune cells from whole blood
• Support the development of complex co-culture assays to explore functional and phenotypic responses of novel therapeutic antibodies
• Support complex scientific research of R&D team by generating data and presenting to the wider team on a regular basis
• Proactively seeking to support delivery from the whole R&D team
Education/Experience:
• PhD in relevant biological discipline or MSc (eg Immunology or Cell Biology) with at least three years of relevant laboratory-based experience.
• Experience working in a company setting (Biotech or Pharma) strongly preferred
• Experience in immunology research across a range of immune cell subtypes. Expertise in innate immunology specifically gamma delta T cell biology would be advantageous
• Strong understanding and experience of biologics drug discovery
• Strong understanding of oncology and/or immunology essential
• Experience of working in a fast moving, dynamic (e.g. small company or start-up) environment preferred
Skills/Competencies:
• Experience in immunology research across a range of cell types including isolating, culturing and performing functional assays with primary human immune cells
• Experience designing flow panels, performing compensation and running multi-colour flow cytometry assays
• Experience performing high throughput (at least 96-well microtiter plates) cell based functional/ imaging-based assays
• Excellent record keeping and attention to detail ensuring accuracy and consistency with a strong focus on data integrity
• Flexible, pragmatic and practical, highly motivated to ensure that studies meet challenging timelines and able to propose practical, compromise solutions to problems
• Willing to take the initiative, planning and implementing work
• Willing to work as part of a small team, engaging constructively with colleagues at all levels to deliver objectives, both for individual work and to help problem solving across the R&D team
• Ability to work independently and collaboratively in a dynamic research environment
• Willing to comply with high Health and Safety standards and Standard Operating Procedures and Policies
• Willing and able to work flexible hours when required.
Organisational Responsibilities:
The Scientist will report into a Senior Scientist in the R&D team. There are no roles reporting into the Scientist role.
Contact:
Please forward your CV to jobs@cytospiretx.com
Notes:
Strictly no agencies.
Candidates must demonstrate they hold the right to work in the UK.
This is a full-time laboratory-based role, 5 days a week in Canary Wharf in London.
Whilst we will attempt to respond to applicants, this may not be possible and if applicants have not heard from us within 6 weeks, they should assume they have not been successful on this occasion.
